CVE-2025-70560: Boltz Boltz Contains An Insecure Deserialization Vulnerability

HIGH
Advisory Identifier: GHSA-fjm6-8xp2-4fwc
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CVSS 8.4
CWE-502
Published
Advisory Summary

CVE-2025-70560 is a HIGH (CVSS 8.4) boltz contains an insecure deserialization vulnerability (CWE-502: Deserialization of Untrusted Data) affecting Boltz libraries in the PyPI ecosystem. The issue involves boltz contains an insecure deserialization vulnerability in its molecule loading functionality. Remediation is available in the latest vendor maintenance releases.

CVE-2025-70560 at a Glance

CVE Identifier CVE-2025-70560
GHSA Identifier GHSA-fjm6-8xp2-4fwc
Severity HIGH
CVSS v3.1 Base Score 8.4
CWE Classification CWE-502: Deserialization of Untrusted Data
Affected Product Boltz
Package Ecosystem PyPI
Published Date
Last Updated

Security Impact

CVSS: 8.4

The security impact metrics below are parsed directly from the CVSS v3.1 vector string (CVSS:3.1/AV:L/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H).

Attack Vector Local (AV:L)
Attack Complexity Low (AC:L)
Privileges Required None (PR:N)
User Interaction None (UI:N)
Scope Unchanged (S:U)
Confidentiality High (C:H)
Integrity High (I:H)
Availability High (A:H)

How to Fix CVE-2025-70560

To remediate this vulnerability, upgrade all affected Boltz dependencies to a patched release. Both direct and transitive dependencies should be checked, as frameworks or security libraries may pull in vulnerable versions transitively.

boltz fixed: Latest secure release 
pip install boltz>=Latest secure release
Verify Direct and Transitive Dependencies

Run the following command in your project directory to verify that all resolved dependencies use the patched release: 

pip show boltz

How to Check if You Are Affected

To determine whether your Python environment is affected by CVE-2025-70560, inspect your installed packages using pip:

pip show boltz

Analyze the terminal output to locate any version of Boltz in your dependency tree. If any resolved version matches the vulnerable ranges listed in the table below (for example, versions earlier than the patched release), your application is affected.

Note: The pip show boltz command checks currently installed packages in your active Python environment.

Technical Details

Vulnerability Mechanism & Technical Analysis

This vulnerability is classified under CWE-502: Deserialization of Untrusted Data, where the product deserializes untrusted data without sufficiently ensuring that the resulting data will be valid. In Boltz, software state validation or input boundaries are circumvented during processing. Review the official source advisory statement below for specific affected components, classes, and reproduction details.

Source Advisory Statement

Boltz 2.0.0 contains an insecure deserialization vulnerability in its molecule loading functionality. The application uses Python pickle to deserialize molecule data files without validation. An attacker with the ability to place a malicious pickle file in a directory processed by boltz can achieve arbitrary code execution when the file is loaded.

CVE-2025-70560 Affected Boltz Versions

1 component(s)
Product / Package Ecosystem Affected Versions Fixed Version
boltz
pypi/boltz
PyPI
≤ 2.0.0

References

NVD — CVE-2025-70560 NVD
https://nvd.nist.gov/vuln/detail/CVE-2025-70560
Boltz Source Repository REPOSITORY
https://github.com/jwohlwend/boltz/issues/600
Boltz Source Repository REPOSITORY
https://github.com/jwohlwend/boltz
Boltz Source Repository REPOSITORY
https://github.com/jwohlwend/boltz/blob/cb04aeccdd480fd4db707f0bbafde538397fa2ac/src/boltz/data/mol.py#L80

Frequently Asked Questions

What is CVE-2025-70560?
CVE-2025-70560 is a security vulnerability in Boltz involving Boltz contains an insecure deserialization vulnerability in its molecule loading functionality under CWE-502: Deserialization of Untrusted Data.
Which Boltz versions are affected?
Affected versions include releases prior to current release patches across affected packages: boltz.
What version fixes CVE-2025-70560?
Upgrading to current release patches (or the latest patched release for your respective branch) resolves the vulnerability.
Is boltz affected?
Yes, boltz is affected in releases prior to Latest secure release. Upgrade your dependency to Latest secure release or later.
What is the CVSS score of CVE-2025-70560?
CVE-2025-70560 has a CVSS v3.1 base score of 8.4 (HIGH) with vector string CVSS:3.1/AV:L/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H.
What CWE is associated with CVE-2025-70560?
CVE-2025-70560 is classified under CWE-502: Deserialization of Untrusted Data (The product deserializes untrusted data without sufficiently ensuring that the resulting data will be valid.).
How can I check PyPI dependencies for CVE-2025-70560?
Run the dependency tree command: 'pip show boltz'. This command lists direct and transitive dependencies in your build configuration so you can verify if a vulnerable version is resolved.
Machine-readable OSV JSON OSV v1.5 Schema
Normalized schema output
View Raw JSON 
{
  "schema_version" : "1.4.0",
  "id" : "GHSA-fjm6-8xp2-4fwc",
  "modified" : "2026-02-04T19:43:50Z",
  "published" : "2026-02-03T18:30:47Z",
  "aliases" : [ "CVE-2025-70560" ],
  "summary" : "Boltz contains an insecure deserialization vulnerability in its molecule loading functionality",
  "details" : "Boltz 2.0.0 contains an insecure deserialization vulnerability in its molecule loading functionality. The application uses Python pickle to deserialize molecule data files without validation. An attacker with the ability to place a malicious pickle file in a directory processed by boltz can achieve arbitrary code execution when the file is loaded.",
  "severity" : [ {
    "type" : "CVSS_V3",
    "score" : "CVSS:3.1/AV:L/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H"
  } ],
  "affected" : [ {
    "package" : {
      "ecosystem" : "PyPI",
      "name" : "boltz"
    },
    "ranges" : [ {
      "type" : "ECOSYSTEM",
      "events" : [ {
        "introduced" : "0"
      }, {
        "last_affected" : "2.0.0"
      } ]
    } ]
  } ],
  "references" : [ {
    "type" : "ADVISORY",
    "url" : "https://nvd.nist.gov/vuln/detail/CVE-2025-70560"
  }, {
    "type" : "WEB",
    "url" : "https://github.com/jwohlwend/boltz/issues/600"
  }, {
    "type" : "PACKAGE",
    "url" : "https://github.com/jwohlwend/boltz"
  }, {
    "type" : "WEB",
    "url" : "https://github.com/jwohlwend/boltz/blob/cb04aeccdd480fd4db707f0bbafde538397fa2ac/src/boltz/data/mol.py#L80"
  } ],
  "database_specific" : {
    "cwe_ids" : [ "CWE-502" ],
    "severity" : "HIGH",
    "github_reviewed" : true,
    "github_reviewed_at" : "2026-02-04T19:43:50Z",
    "nvd_published_at" : "2026-02-03T18:16:17Z"
  }
}